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Brusini L, D'Archivio S, McDonald J, Wickstead B. (2021) Trypanosome KKIP1 dynamically links the inner kinetochore to a kinetoplastid outer kinetochore complex. Frontiers in Cellular and Infection Microbiology. 11:159. pdf_icon
Davies C, Ooi C, Sioutas G, Hall BS, Sidhu H, Butter F, Alsford S, Wickstead B, Rudenko G. (2021) TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei. Nucleic Acids Research. pubmed_iconpdf_icon
Awuah-Mensah G, McDonald J, Steketee PC, Autheman D, Whipple S, D'Archivio S, Brandt C, Clare S, Harcourt K, Wright GJ, Morrison LJ, Gadelha C, Wickstead B. (2021) Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo. PLoS Pathogens. 17:e1009224. pubmed_iconpdf_icon
Steketee PC, Dickie EA, Iremonger J, Crouch K, Paxton E, Jayaraman S, Alfituri OA, Awuah-Mensah G, Ritchie R, Schnaufer A, de Koning HP, Gadelha C, Wickstead B, Barrett MP, Morrison LJ. (2021) Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential drug sensitivity. bioRxiv. 425368. pdf_icon
Brusini L, D'Archivio S, McDonald J, Wickstead B. (2019) Ndc80/Nuf2-like protein KKIP1 connects a stable kinetoplastid outer kinetochore complex to the inner kinetochore and responds to metaphase tension. bioRxiv. 764829. pdf_icon
Abbas AH, Silva Pereira S, D'Archivio S, Wickstead B, Morrison LJ, Hall N, Hertz-Fowler C, Darby AC, Jackson AP. (2018) The structure of a conserved telomeric region associated with variant antigen loci in the blood parasite Trypanosoma congolense. Genome biology and evolution. 10:2458-2473. pubmed_iconpdf_icon
Leonard G, Labarre A, Milner DS, Monier A, Soanes D, Wideman JG, Maguire F, Stevens S, Sain D, Grau-Bové X, Sebé-Pedrós A, Stajich JE, Paszkiewicz K, Brown MW, Hall N, Wickstead B, Richards TA. (2018) Comparative genomic analysis of the 'pseudofungus' Hyphochytrium catenoides. Open Biology. 8:170184. pubmed_iconpdf_icon
D'Archivio S, Wickstead B. (2017) Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes. The Journal of Cell Biology. 216:379. pubmed_iconpdf_icon
Patel JT, Belsham HR, Rathbone AJ, Wickstead B, Gell C, Friel CT. (2016) The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition. Open Biology. 6:160223. pubmed_iconpdf_icon
Roques M, Wall RJ, Douglass AP, Ramaprasad A, Ferguson DJP, Kaindama ML, Brusini L, Joshi N, Rchiad Z, Brady D, Guttery DS, Wheatley SP, Yamano H, Holder AA, Pain A, Wickstead B, Tewari R. (2015) Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes. PLoS Pathogens. 11:e1005273. pubmed_iconpdf_icon
Stanne T, Narayanan MS, Ridewood S, Ling A, Witmer K, Kushwaha M, Wiesler S, Wickstead B, Wood J, Rudenko G. (2015) Identification of the ISWI chromatin remodeling complex of the early branching eukaryote Trypanosoma brucei. The Journal of Biological Chemistry. 290:26954-26967. pubmed_iconpdf_icon
Gadelha C, Zhang W, Chamberlain JW, Chait BT, Wickstead B, Field MC. (2015) Architecture of a host-parasite interface: Complex targeting mechanisms revealed through proteomics. Molecular & Cellular Proteomics. 14:1911-1926. pubmed_iconpdf_icon
Rachel RA, Yamamoto EA, Dewanjee MK, May-Simera HL, Sergeev YV, Hackett AN, Pohida K, Munasinghe J, Gotoh N, Wickstead B, Fariss RN, Dong L, Li T, Swaroop A. (2015) CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies. Human Molecular Genetics. 24:3775-3791. pubmed_iconpdf_icon
Guttery DS, Poulin B, Ramaprasad A, Wall RJ, Ferguson DJP, Brady D, Patzewitz E, Whipple S, Straschil U, Wright MH, Mohamed AMAH, Radhakrishnan A, Arold ST, Tate EW, Holder AA, Wickstead B, Pain A, Tewari R. (2014) Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation. Cell Host & Microbe. 16:128-140. pubmed_iconpdf_icon
Cross GAM, Kim H, Wickstead B. (2014) Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427. Molecular and Biochemical Parasitology. 195:59-73. pubmed_iconpdf_icon
Wheeler RJ, Scheumann N, Wickstead B, Gull K, Vaughan S. (2013) Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis. Molecular Microbiology. 90:1339-1355. pubmed_iconpdf_icon
Poulin B, Patzewitz E, Brady D, Silvie O, Wright MH, Ferguson DJP, Wall RJ, Whipple S, Guttery DS, Tate EW, Wickstead B, Holder AA, Tewari R. (2013) Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite. Biology Open. 2:1160-1170. pubmed_iconpdf_icon
Koumandou VL, Wickstead B, Ginger ML, van der Giezen M, Dacks JB, Field MC. (2013) Molecular paleontology and complexity in the last eukaryotic common ancestor. Critical Reviews in Biochemistry and Molecular Biology. 48:373-396. pubmed_iconpdf_icon
de Leon JC, Scheumann N, Beatty W, Beck JR, Tran JQ, Yau C, Bradley PJ, Gull K, Wickstead B, Morrissette NS. (2013) A SAS-6-Like protein suggests that the Toxoplasma conoid complex evolved from flagellar components. Eukaryotic Cell. 12:1009-1019. pubmed_iconpdf_icon
Guttery DS, Poulin B, Ferguson DJP, Szöőr B, Wickstead B, Carroll PL, Ramakrishnan C, Brady D, Patzewitz E, Straschil U, Solyakov L, Green JL, Sinden RE, Tobin AB, Holder AA, Tewari R. (2012) A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathogens. 8:e1002948. pubmed_iconpdf_icon
Hodges ME, Wickstead B, Gull K, Langdale JA. (2012) The evolution of land plant cilia. The New Phytologist. 195:526-540. pubmed_iconpdf_icon
Daniels J, Gull K, Wickstead B. (2012) The trypanosomatid-specific N-terminus of RPA2 is required for RNA polymerase I assembly, localization and function. Eukaryotic Cell. 11:662-672. pubmed_iconpdf_icon
Sunter J, Wickstead B, Gull K, Carrington M. (2012) A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei. PLoS ONE. 7:e35167. pubmed_iconpdf_icon
Hodges ME, Wickstead B, Gull K, Langdale JA. (2011) Conservation of ciliary proteins in plants with no cilia. BMC Plant Biology. 11:185. pubmed_iconpdf_icon
Wickstead B, Gull K. (2011) The evolution of the cytoskeleton. The Journal of Cell Biology. 194:513-525. pubmed_iconpdf_icon
Kelly S, Wickstead B, Maini PK, Gull K. (2011) Ab Initio identification of novel regulatory elements in the genome of Trypanosoma brucei by Bayesian inference on sequence segmentation. PLoS ONE. 6:e25666. pubmed_iconpdf_icon
Kelly S, Wickstead B, Gull K. (2011) Archaeal phylogenomics provides evidence in support of a methanogenic origin of the Archaea and a thaumarchaeal origin for the eukaryotes. Proceedings of the Royal Society of London. Series B. 278:1009-1018. Supplemental data. pubmed_iconpdf_icon
Wickstead B, Gull K. (2011) The evolutionary biology of dyneins. Chapter 2 (pp88-121). In: Dyneins: Structure, biology and disease. Ed: King S. Academic Press. (no PDF available).
Daniels J-P, Gull K, Wickstead B. (2010) Cell biology of the trypanosome genome. Microbiology and Molecular Biology Reviews. 74:552-569. pubmed_iconpdf_icon
Wickstead B, Carrington JT, Gluenz E, Gull K. (2010) The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic kinesin indicating multiple extra-nuclear roles. PLoS ONE. 5:e15020. Supplemental data. pubmed_iconpdf_icon
Hodges ME, Scheumann N, Wickstead B, Langdale JA, Gull K. (2010) Reconstructing the evolutionary history of the centriole from protein components. Journal of Cell Science. 123:1407-1413. Supplemental data. pubmed_iconpdf_icon
Wickstead B, Gull K, Richards TA. (2010) Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton. BMC Evolutionary Biology. 10:110. Supplemental data. pubmed_iconpdf_icon
Daniels J-P, Kelly S, Wickstead B, Gull K. (2009) Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea. Biology direct. 4:24. Supplemental data. pubmed_iconpdf_icon
Barker AR, Wickstead B, Gluenz E, Gull K. (2008) Bioinformatic insights to the ESAG5 and GRESAG5 gene families in kinetoplastid parasites. Molecular and Biochemical Parasitology. 162:112-122. pubmed_iconpdf_icon
Uzureau P, Daniels J-P, Walgraffe D, Wickstead B, Pays E, Gull K, Vanhamme L. (2008) Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localizations. Molecular Microbiology. 69:1121-1136. pubmed_iconpdf_icon
Wickstead B, Gull K. (2007) Dyneins across eukaryotes: a comparative genomic analysis. Traffic. 8:1708-1721. Supplemental data. pubmed_iconpdf_icon
Gadelha C, Wickstead B, Gull K. (2007) Flagellar and ciliary beating in trypanosome motility. Cell Motility and the Cytoskeleton. 64:629-643. Supplemental data (C Gadelha). pubmed_iconpdf_icon
Kelly S, Reed J, Kramer S, Ellis L, Webb H, Sunter J, Salje J, Marinsek N, Gull K, Wickstead B, Carrington M. (2007) Functional genomics in Trypanosoma brucei: a collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci. Molecular and Biochemical Parasitology. 154:103-109. pubmed_iconpdf_icon
Devaux S, Kelly S, Lecordier L, Wickstead B, Perez-Morga D, Pays E, Vanhamme L, Gull K. (2007) Diversification of function by different isoforms of conventionally shared RNA polymerase subunits. Molecular Biology of the Cell. 18:1293-1301. pubmed_iconpdf_icon
Hammarton TC, Wickstead B, McKean PG. (2007) Cell structure, cell division and the cell cycle. Chapter 8 (pp239-280). In: Trypanosomes: After the Genome. Ed: Barry JD, McCulloch R, Mottram JC, Acosta-Serrano A. Horizon Bioscience. (no PDF available).
Wickstead B, Gull K. (2006) A holistic kinesin phylogeny reveals new kinesin families and predicts protein functions. Molecular Biology of the Cell. 17:1734-1743. Supplemental data. pubmed_iconpdf_icon
Gadelha C, Wickstead B, McKean PG, Gull K. (2006) Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes. Journal of Cell Science. 119:2405-2413. pubmed_iconpdf_icon
Kelly S, Singleton W, Wickstead B, Ersfeld K, Gull K. (2006) Characterization and differential nuclear localization of Nopp140 and a novel Nopp140-like protein in trypanosomes. Eukaryotic Cell. 5:876-879. pubmed_iconpdf_icon
Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Bohme U, Hannick L et al.. (2005) The genome of the African trypanosome Trypanosoma brucei. Science. 309:416-422. pubmed_iconpdf_icon
El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran A, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, Caler E et al.. (2005) The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science. 309:409-415. pubmed_iconpdf_icon
Gadelha C, Wickstead B, de Souza W, Gull K, Cunha-e-Silva N. (2005) Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa. Eukaryotic Cell. 4:516-525. pubmed_iconpdf_icon
Kelly S, Wickstead B, Gull K. (2005) An in silico analysis of trypanosomatid RNA polymerases: insights into their unusual transcription. Biochemical Society Transactions. 33:1435-1437. pubmed_iconpdf_icon
Wickstead B, Ersfeld K, Gull K. (2004) The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes. Genome Research. 14:1014-1024. Supplemental data. pubmed_iconpdf_icon
Becker M, Aitcheson N, Byles E, Wickstead B, Louis E, Rudenko G. (2004) Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast. Genome Research. 14:2319-2329. pubmed_iconpdf_icon
Briggs LJ, Davidge JA, Wickstead B, Ginger ML, Gull K. (2004) More than one way to build a flagellum: comparative genomics of parasitic protozoa. Current Biology. 14:R611-2. pubmed_iconpdf_icon
Vaughan S, Wickstead B, Gull K, Addinall SG. (2004) Molecular evolution of FtsZ protein sequences encoded within the genomes of archaea, bacteria, and eukaryota. Journal of Molecular Evolution. 58:19-29. pubmed_iconpdf_icon
Wickstead B, Ersfeld K, Gull K. (2003) Repetitive elements in genomes of parasitic protozoa. Microbiology and Molecular Biology Reviews. 67:360-375. pubmed_iconpdf_icon
Wickstead B, Ersfeld K, Gull K. (2003) The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number. Nucleic Acids Research. 31:3993-4000. pubmed_iconpdf_icon
Wickstead B, Ersfeld K, Gull K. (2003) The mitotic stability of the minichromosomes of Trypanosoma brucei. Molecular and Biochemical Parasitology. 132:97-100. pubmed_iconpdf_icon
Wickstead B. (2002) PhD thesis: Collected stories from the minichromosomes of Trypanosoma brucei. School of Biological Sciences, University of Manchester, UK. pdf_icon
Wickstead B, Ersfeld K, Gull K. (2002) Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei. Molecular and Biochemical Parasitology. 125:211-216. pubmed_iconpdf_icon
Alsford S, Wickstead B, Ersfeld K, Gull K. (2001) Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei. Molecular and Biochemical Parasitology. 113:79-88. pubmed_iconpdf_icon
Kemp-Harper R, Wickstead B, Wimperis S. (1999) Sodium ions in ordered environments in biological systems: analysis of Na-23 NMR spectra. Journal of Magnetic Resonance. 140:351-362. pubmed_iconpdf_icon
Wickstead B, Grieve SM, Wimperis S. (1998) O-17 NMR of water in ordered environments. Biophysical Chemistry. 73:129-136. pubmed_iconpdf_icon
Taylor RM, Wickstead B, Cronin S, Caldecott KW. (1998) Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1. Current Biology. 8:877-880. pubmed_iconpdf_icon
Grieve SM, Wickstead B, Torres AM, Styles P, Wimperis S, Kuchel PW. (1998) Multiple-quantum filtered O-17 and Na-23 NMR analysis of mitochondrial suspensions. Biophysical Chemistry. 73:137-143. pubmed_iconpdf_icon

2018 2016 2014 2012 2010 2008